Lexaria receives 5 new patents including 2 for diabetes treatment utilizing GLP-1 drugs
KELOWNA, BC / ACCESS Newswire / March 26, 2026 / Lexaria Bioscience Corp. (Nasdaq:LEXX), (the "Company" or "Lexaria"), a global innovator in drug delivery platforms is pleased to provide this update on additional new intellectual property ("IP") granted to the Company as a result of its ongoing research and development ("R&D") programs. This new IP is recognized with the awarding of 5 new patents as detailed below.
"Lexaria is very proud of its internal team for their ingenuity and dedication to pushing scientific boundaries and also to having these achievements recognized by patent offices around the world," said Richard Christopher, CEO of Lexaria. "In particular, given the international race within the GLP-1 industry, our new patents related to diabetes treatments utilizing our proprietary technology in conjunction with already-approved GLP-1 drugs is a notable achievement."
In Lexaria's patent Family #21, Compositions and Methods for Treating Hypertension, we have received 2 new patents (7823051 and 7823052) in Japan, both issued on February 20, 2026 with a term ending on April 25, 2043. Prior to this, Lexaria already had 3 US and 1 European granted patents in this same family.
In our patent Family #24, Compositions and Methods for Treating Epilepsy, we have received 1 new Australian patent (2024205127) issued on February 12, 2026 with a term ending on February 20, 2044. Prior to this, Lexaria already had 6 US; 1 European Union; and 4 previous Australian patents in this patent Family #24.
Finally, in our patent Family #27, Compositions and Methods for Treating Diabetes, we have received 2 new Australian patents (2025205229 and 2024394427) issued on February 12, 2026 with a term ending on December 3, 2044. Prior to this, Lexaria had 2 granted US patents in this newest of our patent families. Lexaria's recent Phase 1b Human Study (GLP-1-H24-4) conducted in Australia provided support in demonstrating the capabilities of our DehydraTECH technology in combination with GLP-1 drugs.
Lexaria's ongoing R&D projects are dedicated to advancing both commercial relationships as well as establishing the incredibly valuable IP in many jurisdictions around the world. Lexaria expects to receive additional patent awards in the future and will continue to report on them from time to time.
About Lexaria Bioscience Corp. & DehydraTECH
DehydraTECH™ is Lexaria's patented drug delivery formulation and processing platform technology which improves the way a wide variety of drugs enter the bloodstream, always through oral delivery. DehydraTECH has repeatedly evidenced the ability to increase bio-absorption, reduce side-effects, and deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 65 patents granted and additional patents pending worldwide. For more information, please visit www.lexariabioscience.com.
CAUTION REGARDING FORWARD-LOOKING STATEMENTS
This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the Company relating to the intended use of proceeds from the offering and relating to the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, market and other conditions, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. The Company provides links to third-party websites only as a courtesy to readers and disclaims any responsibility for the thoroughness, accuracy or timeliness of information at third-party websites. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements or links to third-party websites contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.
INVESTOR CONTACT:
George Jurcic - Head of Investor Relations [email protected] Phone: 250-765-6424, ext 202
Early-stage discussions with several multinational pharmaceutical companies currently underway
KELOWNA, BC / ACCESS Newswire / March 24, 2026 / Lexaria Bioscience Corp. (NASDAQ:LEXX), (the "Company" or "Lexaria"), a global innovator in drug delivery platforms provides this update of developments within the glucagon-like peptide-1 ("GLP-1") market.
Lexaria has been listening and responding to the concerns of those using GLP-1 drugs, who overwhelmingly indicate their preference for oral versus injected delivery and who are desperately seeking safer options whose side effects do not make them feel sick. This has driven Lexaria's mission to develop better tolerated oral GLP-1 capsule and tablet alternatives. After far-reaching proprietary formulation advancements and the establishment of intellectual property in 2024 and 2025, Lexaria is currently developing additional enhancements to its DehydraTECH GLP-1 platform that we are hopeful could instigate commercial development with leading industry partners.
Lexaria first began reporting on the momentum within the fast-moving GLP-1 drug sector during 2023. Growth in the sector has been, if anything, even more significant than we anticipated at the time and has supported our business strategy of pursuing opportunities within the GLP-1 market. Examples of this growth and the challenges abound:
Eli Lilly's tirzepatide is expected to be the #1-selling drug in the world for 2026, with revenue estimated at $45 billion. Novo Nordisk's® semaglutide - previously the #1 GLP-1 drug - is expected to generate nearly $40 billion in revenue in 2026. In concert with the sector growth, many analysts have significantly increased their revenue projections. TD Cowen® raised their previous 2030 sales forecast from $101 billion to $139 billion, Roots Analysis is forecasting sales of $180 billion by 2035, while UBS Investment Bank® expects 2029 GLP-1 sales to reach $126 billion.
Injected GLP-1 drugs often produce very similar results to oral GLP-1 drugs. For instance, in a 2021 study, patients who took once-weekly semaglutide injections lost an average of ~15% of their body weight - as compared to a 2023 study of oral semaglutide which also resulted in patients losing ~15% of their body weight. However, regardless of the mode of administration, most patients using GLP-1 drugs experience unwanted side effects (or adverse events) that are primarily gastrointestinal ("GI") in nature. In the 2021 study of injected semaglutide, 74% of patients experienced GI side effects, whereas in the 2023 study of oral semaglutide, 80% of patients experienced GI side effects.
In a very large 6-year study of over 125,000 patients, it was reported that 46.5% of patients with, and 64.8% of patients without, type 2 diabetes, discontinued use of their GLP-1 drugs within 1 year. Equally interesting, 47.3% of patients with, and 36.3% of patients without, type 2 diabetes subsequently reinitiated use of GLP-1 medications within 1 year. Given that GLP-1 drugs were initially approved for use by diabetics, it is not surprising that those with this serious medical condition were less likely to discontinue use, and more likely to reinitiate subsequent use, than those people who used GLP-1 primarily for weight loss benefits.
From a strategic perspective, Lexaria understood that losing roughly half your customers could not have been a welcome development for the manufacturers of GLP-1 drugs. That's why we focused on the goals of improving patient experiences via the preferred oral delivery method whilst preserving the efficacy of the underlying medication. To do so, we had to better understand the needs of the market to bolster our business case.
In a survey of 2,173 patients who discontinued the use of GLP-1 drugs, a majority of the patients identified two main areas of concern: the GI-related discomfort or the negativity associated with injections:
11% of American adults and 8% of Canadian adults are currently taking a GLP-1 prescription
Extrapolated, this suggests that 28M+ American adults and 3M+ Canadian adults are currently using GLP-1 prescriptions
12% of Americans and 6% of Canadians are interested in taking a GLP-1 prescription
71% of Americans and 58% of Canadians cite weight loss as a primary reason for their interest in GLP-1 drugs
Given that nearly two-thirds of GLP-1 customers focused on weight loss tend to discontinue use of the drugs within the first year, Lexaria knew that our attempts to improve the patient experience could provide a profoundly positive business case. With less than 5% of the entire 2025 GLP-1 revenue attributed to the sole oral drug, Rybelsus®, Lexaria's management understood earlier than most, both the risk and the tremendous opportunity in pursuing such a relatively small portion of the market at that time; our strategy was and remains forward looking.
By the beginning of 2025, the sector was buzzing with anticipation of Pfizer's® orally-delivered GLP-1 candidate, danuglipron, which had shown great promise in Phase I and II studies. Then on April 14, 2025, Pfizer reported that they were discontinuing development of danuglipron because in an ongoing Phase III study of 1,400 people, one person experienced elevated liver enzymes that resolved after its discontinuation. Pfizer had little choice but to forego a potential multi-billion-dollar drug blockbuster because the adverse events were simply not acceptable. This was a devastating blow to Pfizer and to all those hoping for a new oral alternative in GLP-1.
But industry development of GLP-1 drugs has not ended. If anything, it has only intensified. In May of 2025, it was reported that 39 new GLP-1 medications were under development. Companies such as Viking Therapeutics® and Structure Therapeutics® are both pursuing oral GLP-1 drug candidates.
Similarly, Eli Lilly is developing orforglipron, a small-molecule GLP-1 candidate. The New England Journal of Medicine® published an article detailing the outcomes of orforglipron, being investigated as an oral treatment for obesity. This Phase III multinational study provided average weight loss of up to 11.2% at the maximum dose by the completion of the 72-week study. Roughly 5% - 10% of the patients in the study discontinued use due to adverse events. This drug has not yet been approved for use by the FDA, but that approval is expected as soon as April 2026. In anticipation of same, Eli Lilly has reportedly already built a pre-launch drug inventory of $1.5 billion, to minimize or eliminate shortages after approval.
While orforglipron has shown in studies to be slightly more effective at reducing body weight and reducing blood sugar levels than semaglutide, "Orforglipron showed higher rates of adverse side effects such as nausea, vomiting and other gastrointestinal issues compared with semaglutide. More people discontinued orforglipron during the trial than those who stopped taking semaglutide, too." (Scientific American®)
Novo Nordisk's semaglutide received FDA approval for an oral tablet for weight loss in January 2026 and reached over 26,000 prescriptions within two weeks of launch. Novo Nordisk expects oral GLP-1 tablets to represent over 33% of the GLP-1 market by 2030, compared to less than 5% realized in 2025. Goldman Sachs® is forecasting that oral GLP-1s will capture 24% of the 2030 market for obesity drugs.
These forecasts imply that oral GLP-1 markets for all conditions could represent a $40 billion to $45 billion annual market within just 4 years: a stunning anticipated growth curve that represents what might truly be called a once-in-a-lifetime market opportunity.
According to PRC,® "the window to shape the oral GLP 1 market is open now-and it will not remain open for long. Decisions made today across manufacturing and commercialisation will determine which companies are best positioned as these therapies move from promise to scale. As the landscape evolves rapidly, early, deliberate investment in the right capabilities and strategic partnerships will be critical to securing a leadership position."
Lexaria is executing its strategy of developing must-have technology that delivers solutions to meet patient's #1 requests: an effective GLP-1 drug delivered orally with reduced side effects.
Our 2026 R&D and business development plans are designed to foster commercial relationships with pharmaceutical companies around the world, including those located in heavily populated countries such as India, China, and Brazil where key semaglutide patents expire in 2026, opening new opportunities for generic GLP-1 candidates utilizing Lexaria's patented DehydraTECH technology. Lexaria is currently in early-stage discussions with several multinational pharmaceutical companies related primarily but not exclusively to our work in GLP-1.
About Lexaria Bioscience Corp. & DehydraTECH DehydraTECH™ is Lexaria's patented drug delivery formulation and processing platform technology which improves the way a wide variety of drugs enter the bloodstream, always through oral delivery. DehydraTECH has repeatedly evidenced the ability to increase bio-absorption, reduce side-effects, and deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with over 60 patents granted and additional patents pending worldwide. For more information, please visit www.lexariabioscience.com.
CAUTION REGARDING FORWARD-LOOKING STATEMENTS This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the Company relating to the intended use of proceeds from the offering and relating to the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, market and other conditions, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. The Company provides links to third-party websites only as a courtesy to readers and disclaims any responsibility for the thoroughness, accuracy or timeliness of information at third-party websites. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements or links to third-party websites contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.
INVESTOR CONTACT: George Jurcic - Head of Investor Relations [email protected] Phone: 250-765-6424, ext 202
Exciting new human and animal studies designed to enhance business opportunities
KELOWNA, BC / ACCESS Newswire / March 4, 2026 / Lexaria Bioscience Corp. (Nasdaq:LEXX), (the "Company" or "Lexaria"), a global innovator in drug delivery platforms announces the beginning of its 2026 research and development program (the "2026 R&D Program") designed to broaden pharmaceutical, intellectual property ("IP"), and business development opportunities through new and improved formulations.
Information on 3 new studies from the 2026 R&D Program which are representative of the Company's primary areas of focus during at least the first three quarters of the calendar year, is being released today, however these studies do not necessarily encompass the entire 2026 R&D Program.
"Our 2026 R&D Program might be the most focused on practical results that the Company has ever conducted," stated Richard Christopher, CEO of Lexaria. "These studies are specifically concentrated on increasing the likelihood of pharma industry partnerships and the creation of new intellectual property," continued Mr. Christopher. "Some of this work must intentionally remain obscure at this time since, if successful, it could likely lead to expanded new IP and patent development."
Human Study GLP-1-H26-7
With study design nearing completion, this is expected to be a 5-week parallel group study consisting of 3 different arms with primary goals of establishing safety and tolerability, as well as pharmacokinetic ("PK") evaluation, comparing salcaprozate sodium ("SNAC")-inclusive DehydraTECH-semaglutide tablet and capsule compositions to the recently launched, commercially available Wegovy® semaglutide tablets under fasted pre-dose conditions.
Generally speaking, this study will evaluate differences between DehydraTECH capsules traditionally optimized for intestinal absorption and DehydraTECH tablets experimentally optimized for primarily stomach absorption. It will also evaluate the performance of a SNAC-enabled DehydraTECH-semaglutide formulation that was not previously included in Lexaria's Phase I Human Study conducted in Australia in 2025.
Study GLP-1-H26-7 will also be designed to expand upon the findings of Human Pilot Study #1 which delivered exciting PK and safety results with an earlier iteration of SNAC-inclusive DehydraTECH-semaglutide capsules, but was limited to a single day of dosing and was, thus, incapable of achieving so-called steady-state PK results as will be targeted here. Study GLP-1-H26-7 will also be much more robust than Human Pilot Study #1, with roughly 30 subjects expected to be enrolled in each of the study arms concentrating on the tablet comparisons, and 15 subjects in the capsule study arm. While the larger study sample size increases costs, it also improves the prospective statistical reliability of the data generated, hopefully sufficient to encourage industry partnering if successful.
Lexaria is aggressively working with its third-party service providers with the intent of beginning recruitment in this study as early as April. Ethics board submissions will be made as soon as possible. The Company will provide public updates when ethics board approval has been achieved. A final study report should be expected in Q4, 2026. (All dates herein referring to calendar 2026.)
Animal Studies
Lexaria is also progressing rapidly with study design for 2 animal studies. The Company typically conducts animal study work with two main objectives: first, to establish scientific evidence supporting new concepts, procedures and formulations intended to facilitate the development of new IP through the development and filing of patent applications; and second, to test wide varieties of conditions and formulations to narrow down choices prior to potential future corroborating human study work.
Animal Study GLP-1-A26-1
Animal Study GLP-1-A26-1 is expected to be a large, single-dose study with between 8-11 different arms. Blood samples are expected to be drawn over an 8-24-hour post-dose period to quantify the PK performance of the active ingredients. We currently expect to test various SNAC-inclusive DehydraTECH-semaglutide formulations with prospective formulation performance enhancements from our earlier glucagon-like peptide-1 ("GLP-1") related work; and in separate arms, test various DehydraTECH-cannabidiol formulations where similar enhancements may be beneficial for Lexaria's cannabidiol therapeutic program pursuits.
Brain samples will also be taken since DehydraTECH has, in the past, evidenced apparent superior absorption of active ingredients into brain tissue, an area of intense interest due to the fact that GLP-1 drug performance is increasingly understood to include or even depend upon involvement of brain neurochemistry, thus making brain biodistribution vital.
A primary goal of this study will be to discover whether new and different formulation enhancements contemplated by Lexaria might enhance PK performance of either of these drug classes. Given the expected unique formulations and proprietary internal understanding of DehydraTECH capabilities, Lexaria is exploring, among other study objectives, whether it might be able to create new IP previously unknown to industry in the hopes of developing valuable proprietary technology that could be used in the oral delivery of GLP-1 and potentially other drugs.
Animal Study GLP-1-A26-1 is anticipated to begin by Q2, 2026 with a final study report expected near the end of Q3, 2026.
Animal Study GLP-1-A26-2
Animal Study GLP-1-A26-2 is expected to be a large, single-dose study with between 14-18 different arms. This study will be focused on the delivery of DehydraTECH enhanced retatrutide and amycretin, both GLP-1 drugs that Lexaria has never studied before. The inclusion of retatrutide will mark the first time that that Company has worked with a triple agonist which targets GLP-1, glucose-dependent insulinotropic polypetide ("GIP") and glucagon receptors. Also unique to Lexaria's historical research, some of the study arms will be comparing the PK performance of test articles placed endoscopically in the intestine versus being swallowed thus targeting the stomach, in order to compare and contrast formulation functionality and performance in these distinct drug delivery dosing regions gastrointenstinally.
As with Animal Study GLP-1-A26-1, a number of different formulations will also be evaluated to provide us with guidance on potential performance enhancements that may result from either the different formulation compositions or from the different routes of absorption. Blood samples are expected to be drawn over a 24-hour post-dose period to quantify the PK performance of the active ingredients.
Animal Study GLP-1-A26-2 is also anticipated to begin by Q2, 2026 with a final study report expected near the end of Q3, 2026.
Each of the above noted studies will be conducted by independent third-party service providers and individually announced with additional details once they are ready to proceed. Final designs and details are still being completed and may vary slightly from the details provided herein. Additional R&D work, not yet disclosed, may be completed during 2026.
About Lexaria Bioscience Corp. & DehydraTECH
DehydraTECH™ is Lexaria's patented drug delivery formulation and processing platform technology which improves the way a wide variety of drugs enter the bloodstream, always through oral delivery. DehydraTECH has repeatedly evidenced the ability to increase bio-absorption, reduce side-effects, and deliver some drugs more effectively across the blood brain barrier. Lexaria operates a licensed in-house research laboratory and holds a robust intellectual property portfolio with 60 patents granted and additional patents pending worldwide. For more information, please visit www.lexariabioscience.com.
CAUTION REGARDING FORWARD-LOOKING STATEMENTS
This press release includes forward-looking statements. Statements as such term is defined under applicable securities laws. These statements may be identified by words such as "anticipate," "if," "believe," "plan," "estimate," "expect," "intend," "may," "could," "should," "will," and other similar expressions. Such forward-looking statements in this press release include, but are not limited to, statements by the Company relating to the intended use of proceeds from the offering and relating to the Company's ability to carry out research initiatives, receive regulatory approvals or grants or experience positive effects or results from any research or study. Such forward-looking statements are estimates reflecting the Company's best judgment based upon current information and involve a number of risks and uncertainties, and there can be no assurance that the Company will actually achieve the plans, intentions, or expectations disclosed in these forward-looking statements. As such, you should not place undue reliance on these forward-looking statements. Factors which could cause actual results to differ materially from those estimated by the Company include, but are not limited to, market and other conditions, government regulation and regulatory approvals, managing and maintaining growth, the effect of adverse publicity, litigation, competition, scientific discovery, the patent application and approval process, potential adverse effects arising from the testing or use of products utilizing the DehydraTECH technology, the Company's ability to maintain existing collaborations and realize the benefits thereof, delays or cancellations of planned R&D that could occur related to pandemics or for other reasons, and other factors which may be identified from time to time in the Company's public announcements and periodic filings with the US Securities and Exchange Commission on EDGAR. The Company provides links to third-party websites only as a courtesy to readers and disclaims any responsibility for the thoroughness, accuracy or timeliness of information at third-party websites. There is no assurance that any of Lexaria's postulated uses, benefits, or advantages for the patented and patent-pending technology will in fact be realized in any manner or in any part. No statement herein has been evaluated by the Food and Drug Administration (FDA). Lexaria-associated products are not intended to diagnose, treat, cure or prevent any disease. Any forward-looking statements contained in this release speak only as of the date hereof, and the Company expressly disclaims any obligation to update any forward-looking statements or links to third-party websites contained herein, whether as a result of any new information, future events, changed circumstances or otherwise, except as otherwise required by law.
INVESTOR CONTACT:
George Jurcic - Head of Investor Relations [email protected] Phone: 250-765-6424, ext 202
